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Canada’s vaccination program could switch to a gender-neutral, single-dose human papillomavirus (HPV) vaccination approach that could eliminate cervical cancer, new modeling suggests in Canadian Medical Association Journal has been done.
“Our results have important policy implications for Canada and other similar high-income countries that are considering whether to switch to a single-dose HPV vaccine,” said Université Laval, Quebec, full professor. , writes Dr. Mark Brisson, head of the mathematics department. Infectious Disease Modeling and Health Economics Laboratory, Laval University Research Center, Université du Québec.
Countries around the world are considering whether to move from two-dose to one-dose HPV vaccinations after the World Health Organization’s Expert Strategic Advisory Group on Immunization recommended a 2022 recommendation based on clinical trial evidence. . Human papillomavirus can cause cervical cancer and other diseases.
Researchers in Ontario and Quebec are investigating various treatments based on one-dose and two-dose approaches to inform recommendations from the National Advisory Committee on Immunization of Canada and the Quebec Immunization Committee. I modeled the scenario.
The research group found that one dose of the gender-neutral vaccine could prevent the same number of cervical cancers as two doses, provided the vaccine remains highly protective at the age of peak sexual activity. I discovered it.
“Even in the most pessimistic scenario, all one-dose vaccination scenarios were predicted to be a substantially more efficient use of vaccine doses than two-dose vaccinations. ” all of the scenarios were projected to lead to the elimination of cervical cancer in Canada between 2032 and 2040,” the authors write.
This approach makes more efficient use of vaccine doses and is predicted to help eliminate cervical cancer in Canada.
“The COVID-19 pandemic has impacted HPV vaccination in Canada, particularly among vulnerable populations, due to the potential economic savings from switching to a one-dose vaccine and the flexibility of its program. Investments could be made to increase vaccination coverage in areas and regions with suboptimal coverage.” Targeting subgroups with high HPV burden to mitigate the impact of the pandemic on programs and reduce inequalities. We need to target it,” said Dr. Chantal Saubergeau, a community health expert and infectious disease consultant at Quebec’s National Institute of Public Health.
Periodic monitoring of single-dose protection is recommended to detect signs of decreased protection.
Further information: Switching from a two-dose to a single-dose program in a gender-neutral routine vaccination program against human papillomavirus in Canada: a mathematical modeling analysis, Canadian Medical Association Journal (2024). DOI: 10.1503/cmaj.240787
Provided by Canadian Medical Association Journal
Citation: New model shows potential for switching to a single-dose gender-neutral approach for human papillomavirus vaccination (October 7, 2024) https://medicalxpress.com/news/2024-10-potential -human-papillomavirus- Retrieved on October 7, 2024 vaccination-dose.html
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