overview
This report provides a detailed assessment of the potential role of vaccines in mitigating antimicrobial resistance (AMR). This paper outlines the importance of vaccines as important tools to prevent infections, reduce the spread of resistant strains, and reduce dependence on antibiotics. Historically, the focus has been primarily on the use of vaccines to prevent infectious diseases, and the role of vaccines in mitigating AMR has not been fully recognized.
This report is unique in that it comprehensively evaluates 44 vaccines targeting 24 pathogens, covering both licensed vaccines and those in development. It incorporates a powerful methodology to estimate the potential impact of these vaccines on AMR-related health outcomes, antibiotic use, and economic costs. The report is unique in its detailed modeling of the burden avoided by vaccines and the feasibility of developing each pathogen. The findings highlight the important role that vaccines must play in national and global AMR mitigation strategies.