7:28pm (Eastern Time)
Bottom line: Chiefs defense remains elite, but 49ers have more injuries.
This live broadcast has ended
7:19pm (Eastern Time)
Tom Brady impressed with Chiefs’ young defense
7:17pm (Eastern Time)
49ers star OL Trent Williams leaves the game due to erratic play.
7:14pm (Eastern Time)
Mecole Hardman finds the end zone again vs. 49ers
7:05pm ET
Brock Purdy leads 49ers to red zone, gets picked again
6:49pm (Eastern Time)
Patrick Mahomes’ foot sets up decisive touchdown
6:37pm (Eastern Time)
Brock Purdy makes his second interception of the game.
6:28pm (Eastern Time)
Which QB can find the next gear?
6:20pm (Eastern Time)
Tom Brady’s advice to 49ers: ‘Run the football’
6:16pm (Eastern Time)
The aggressiveness of the Purdies and 49ers paid off with the first TD of the game.
6:11pm (Eastern Time)
Patrick Mahomes shoots again.
6:07pm (Eastern Time)
Halftime: Red zone run differential in games so far with Chiefs leading
5:56pm (Eastern Time)
Brandon Aiyuk leaves with knee injury just before halftime
5:48pm (Eastern Time)
Ricky Pearsall gets a standing ovation after making his first NFL catch.
5:36pm (Eastern Time)
49ers offense continues to be in turmoil
5:31pm (Eastern Time)
Kareem Hunt’s second TD on an even drive extends the Chiefs’ lead.
5:15pm (Eastern Time)
First, Kansas City in the end zone!
5:05pm (Eastern Time)
Tom Brady: “It’s hard to score points on defense”
4:56pm (Eastern Time)
Which attack can attack first?
4:55pm (Eastern Time)
49ers return the favor by targeting Mahomes, and Brady breaks it up.
4:42pm (Eastern Time)
Justin Reid drafts Brock Purdy
4:40pm (Eastern Time)
defense stands early
4:09pm (Eastern Time)
GOAT QB, WR holding the court before the game
4:02pm (Eastern Time)
Preview: These aren’t last year’s Chiefs and 49ers
This live broadcast began at 7:57 PM ET