October 11, 2024
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The Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine received $4.7 million from the NIH to develop imaging technology to detect changes in capillary function and help diagnose cerebral small vessel disease.
Jianhua “Jay” Wang, M.D., professor of ophthalmology at Bascom Palmer Eye Institute, will lead a team of scientists, clinical researchers and computer experts in this effort, according to a university press release.
Bascom Palmer Eye Institute researchers have been awarded $4.7 million from the NIH to develop an imaging technique that reads capillary blood flow through the retina. Image: Adobe Stock
“Using the eye as a window into the central nervous system, Dr. Wang will create an advanced non-invasive ophthalmic imaging device that reads capillary blood flow through the retina and establishes new biomarkers for cerebral small vessel disease. Eduardo said: Alfonso, M.D., director and director of the institute, said in a release. “This is groundbreaking research that will benefit thousands of patients.”
Current imaging techniques such as MRI can detect blood flow in large blood vessels, but not small capillaries, the study said. Cerebral small vessel disease contributes to cognitive impairment and dementia, so improved imaging could help detect central nervous system disorders early.
With NIH funding, Wang and colleagues are developing a high-speed, wide-field adaptive optics near confocal ophthalmoscope to read capillary blood flow through the retina and help establish new biomarkers for cerebral small vessel disease. .
“This is a complex problem, and we have assembled a diverse team of scientists to solve it,” Wang said in the release. “We have experts in neurology, neuro-ophthalmology, engineering, computer science, and many other fields. The potential for this device over the next 20 to 30 years is huge. Together, we We are developing a device that can reveal the health of the brain’s capillaries and provide much-needed insight into these difficult neurological diseases.”
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