Last season, teams that trailed by seven points or more went 15-50, but this year they are 7-2. This year’s Touchdown Plus Dogs’ winning percentage of 77.8% is the best five-week mark since the 1970 merger, so keep that in mind when making NFL bets for Week 6. There is one big underdog on the NFL’s Week 6 schedule as Philadelphia is an 8.5 point favorite against Cleveland with a low over-under of 42 games. Philadelphia could be lethargic as they could be eliminated by a bye against a Browns team that is desperate for a win. You can also seek NFL betting advice for both NFL straight-up picks and NFL vs. spread picks. Before you make your Week 6 NFL picks or NFL parlays, be sure to check out what SportsLine Senior Analyst Larry Hartstein has to say.
A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Las Vegas sources with an analytical approach honed while working at Pro Football Focus. Hartstein went 53-34-3 at the 2022 Westgate Las Vegas Supercontest, finishing tied for 52nd ATS (out of 1,598 entries). His weekly Las Vegas contest picks are the basis of his NFL Best Bet column, which is 84-57-3 (59.6%, +20.90 units) since the start of 2022.
In Week 6, Hartstein confidently identified three best bets. If you are successful in parlaying his picks, you can expect a payout of almost 6-1. You can see Hartstein’s Week 6 NFL picks only on SportsLine.
NFL’s top Week 6 picks
It’s safe to say that Hartstein loves the Titans (-2.5, 42.5), who will be covering the AFC South at home against the Colts. This is the perfect schedule spot for a Titans team that won a bye last week against a depleted Colts team that had just handed the Jaguars their first win. Trevor Lawrence (371 passing yards) and Tank Bigsby (101 rushing yards) both set career highs against Indianapolis. Indianapolis ranked last in the NFL in yards allowed, second in rushing yards allowed and fourth in passing yards.
Meanwhile, the Titans unlocked their running game ahead of the bye, rushing for a season-high 142 yards. Additionally, kicker Nick Folk is a perfect 15/15 on all attempts, and the Titans have committed the second fewest penalties this season. Add that Hartstein still likes Tennessee, even though the Titans have covered their last six games with byes and the line has gone from +1.5 to -2.5. Check out which other potential NFL parlay picks here.
How to Make an NFL Parlay for Week 6
Hartstein also jumped on two other NFL games, including rooting for a shocking underdog whose opponent was missing a “difference-maker” due to injury. See Hartstein’s Week 6 NFL best bets and parlays only on SportsLine.
What is Hartstein’s top pick in the NFL for Week 6? And which NFL matchups should he be targeting for a chance at an epic 6-1 payout? Visit SportsLine now to find out more about the NFL Check out the best NFL bets for Week 6 from Las Vegas experts who have 20.90 units on ATS picks.